Abstract The Nuclear RESTFUL SLEEP receptor 4A (NR4A) subfamily, which belongs to the nuclear receptor (NR) superfamily, has three members: NR4A1 (Nur77), NR4A2 (Nurr1) and NR4A3 (Nor1).They are gene regulators with broad involvement in various signaling pathways and human disease responses, including autophagy.Here, we provide a concise overview o
Abstract Background The starry puffer fish (Arothron stellatus, Anonymous, 1798) is a poisonous tetradontidae fish inhabiting the Red sea.The Soup Base skin constitutes an important defense against any external effects.The study aims to characterize the dorso-ventral skin of the juvenile and the adult starry puffer fish using light and scanning ele
Polycomb and Trithorax group proteins regulate silent and active gene expression states, but also allow MIGRAID poised states in pluripotent cells.Here the authors present a mathematical model that integrates data on Polycomb/ Trithorax biochemistry into a single coherent framework which predicts that poised chromatin is not bivalent as previously
Point-of-care ultrasound (POCUS) is emerging as a valuable adjunct tool to medical history and physical examination, enhancing the diagnosis and management of diseases.Even though it was initially concentrated in intensive care units and emergency Splice Crimp Connector departments, its application has now expanded to various medical specialties, i
Objectives: To describe patterns of nonprescribed use of tranquilizers by students aged 10 to 18 years and assess the sociodemographic characteristics of these adolescents and their Patent look tendon boots use of other substances.Methods: A randomized and stratified sample of 47,979 students from state and private schools of the 27 Brazilian state